If you’re diving into the world of luxury skincare, two powerhouse products are likely to catch your eye: SkinMedica TNS Advanced+ Serum and Augustinus Bader The Serum Nomad. Both are widely celebrated for their science-driven, high-performance formulations aimed at reversing visible signs of aging. While they may appear similar at first glance, these serums differ significantly in formulation, target concerns, and price point.
In this detailed comparison, we’ll explore how each serum performs, what sets them apart, and which one might be the perfect fit for your skincare goals.
What You’ll Learn:
- What are SkinMedica TNS Advanced+ Serum and Augustinus Bader The Serum Nomad?
- Ingredient comparison
- Texture and application differences
- Ideal usage routines
- Price comparison
- Final verdict: Which serum is best for your skin?
Overview of the Products
SkinMedica TNS Advanced+ Serum
SkinMedica, a leading name in dermatologist-developed skincare, is known for its use of cutting-edge science and growth factors. One of its top-rated products is the TNS Advanced+ Serum, a next-generation formula developed to address visible signs of aging.

This advanced serum is designed to reduce fine lines, wrinkles, sagging skin, and uneven texture. As an upgraded version of their previous TNS-MR formula, it includes clinically backed ingredients aimed at improving elasticity, brightening skin tone, and reducing dark spots.
Augustinus Bader The Serum Nomad
Founded by stem cell scientist Dr. Augustinus Bader, this luxury skincare brand has quickly become a cult favorite. The Serum Nomad is a potent, fast-absorbing treatment created to support hydration, protection, nourishment, and skin renewal.

Its formula targets a wide range of skin issues including dehydration, aging, pigmentation, and environmental damage, all while encouraging the skin’s natural regenerative process. It’s a favorite among those seeking a radiant, healthy glow with a science-backed formula.
Ingredient Comparison
SkinMedica TNS Advanced+ Serum
This serum centers around Tissue Nutrient Solution (TNS®)—a proprietary mix of growth factors, peptides, and antioxidants designed to support collagen production and skin rejuvenation. Key ingredients include:
- Growth factors for reducing fine lines and improving skin firmness
- Vitamins C & E to neutralize free radicals
- Alpha-arbutin for brightening and reducing dark spots
- Spanish marine extract & green microalgae to support collagen synthesis
- Fragrance-free & paraben-free formula suitable for most skin types
This formula is particularly effective for mature, sensitive, dry, oily, or combination skin types looking to restore youthful texture and tone.
Augustinus Bader The Serum Nomad
This serum is powered by the brand’s proprietary TFC8® complex, a blend of natural amino acids, high-grade vitamins, and synthesized molecules found naturally in the skin. Additional key ingredients include:
- Vitamin C to boost collagen, brighten skin, and defend against oxidative stress
- Polysaccharide Moisture Complex for deep hydration and moisture retention
- Squalane for skin softness and moisture balance
- Sodium Hyaluronate to plump and smooth fine lines
- Pomegranate & Edelweiss Extract to combat premature aging
- Rich Brain oil to nourish and support skin regeneration
This formula is suitable for all skin types, including sensitive and dehydrated skin, and addresses a broader range of issues including inflammation and environmental damage.
Texture & Consistency
SkinMedica TNS Advanced+ Serum
- Texture: Lightweight and quickly absorbed
- Finish: Matte, non-greasy, and colorless
- Fragrance: Fragrance-free for sensitive skin users
It’s designed to deliver active ingredients efficiently without leaving a heavy or sticky residue.
Augustinus Bader The Serum Nomad
- Texture: Lightweight, milky concentrate
- Finish: Fast-absorbing with a silky-smooth feel
- Fragrance: Mild and clean, not overpowering
Its airy texture hydrates deeply and is ideal for layering or standalone use, offering a luxurious skincare experience without greasiness.
How to Use Each Serum
SkinMedica TNS Advanced+ Serum
- Step in routine: Use after cleansing and toning
- Application: Dispense a small amount and gently apply to the face, neck, and décolleté
- Recommended for: Targeting deep wrinkles, skin sagging, and uneven tone
With consistent use, some users have noticed improved elasticity and a reduction in deeper wrinkles within 8 weeks.
Augustinus Bader The Serum Nomad
- Step in routine: Apply to clean, dry skin before moisturizer
- Application: Smooth in upward, sweeping motions across the face, neck, and chest
- Recommended for: Hydration, redness, pigmentation, aging, and environmental stressors
Many users report that it’s so hydrating, they skip moisturizer altogether, thanks to its all-in-one benefits.
Price Comparison
Product | Size | Approx. Price |
SkinMedica TNS Advanced+ Serum | 30ml | $236 – $295 |
Augustinus Bader The Serum Nomad | 30ml refill | $375 |
Full size | $550 |
Summary: Augustinus Bader’s The Serum Nomad is significantly more expensive than SkinMedica TNS Advanced+ Serum. However, it offers a more comprehensive ingredient profile and multi-targeted benefits.
Final Verdict: Which One Should You Choose?
Choose SkinMedica TNS Advanced+ Serum if:
- Your main goals are wrinkle reduction, firming, and even skin tone
- You prefer a lightweight, fragrance-free serum with dermatologist-backed growth factors
- You want a targeted solution for mature or aging skin
Opt for Augustinus Bader The Serum Nomad if:
- You’re looking for a luxurious, all-in-one serum that addresses hydration, radiance, aging, and protection
- Your skin is sensitive, dry, or easily affected by environmental stressors
- Budget is not a constraint, and you’re seeking a cutting-edge formulation backed by stem cell science
Final Thoughts
Both SkinMedica TNS Advanced+ Serum and Augustinus Bader The Serum Nomad are exceptional products backed by science and innovation. Your choice will ultimately depend on your skin’s specific needs, ingredient preferences, and budget.
- Choose SkinMedica for targeted anti-aging treatment focused on visible signs like wrinkles and sagging.
- Choose Augustinus Bader for a broader, more luxurious solution that hydrates, protects, and rejuvenates from within.
Either way, both serums bring transformative benefits to your skincare regimen, helping you achieve a healthier, more radiant complexion.