Finding the right skincare product can feel overwhelming with so many options available. Two highly praised serums, Estee Lauder Advanced Night Repair and Shiseido Ultimune Power Infusing Concentrate, have consistently stood out in the skincare industry for their impressive results and trusted brand heritage. But what exactly sets them apart?
In this article, we’ll explore both serums in depth to help you determine which one aligns best with your skin type and goals.
What We’ll Cover:
- Overview of both products
- Key ingredients comparison
- Texture and absorption differences
- Best usage practices
- Price breakdown
- Final buying guide
Overview: Estee Lauder vs Shiseido
Estee Lauder Advanced Night Repair
Estee Lauder is a renowned American luxury skincare brand established in 1946. Known for innovative, science-backed formulations, the brand aims to create luxurious products that deliver noticeable results. One of its most iconic offerings is Advanced Night Repair, a nighttime serum celebrated for its ability to combat visible signs of aging and improve skin texture and tone.

Shiseido Ultimune Power Infusing Concentrate
Founded in 1872, Shiseido is one of Japan’s oldest and most respected skincare brands. Known for fusing Eastern traditions with advanced skincare science, Shiseido has earned a global reputation. Ultimune Power Infusing Concentrate is a flagship product, designed to enhance the skin’s resilience and defense mechanisms while promoting hydration and smoother texture.

Both serums cater to users seeking youthful, radiant skin, but they work in different ways. Let’s examine the differences more closely.
Ingredient Comparison
Estee Lauder Advanced Night Repair
This oil-free serum contains Tripeptide-32, which supports the skin’s natural circadian rhythm for optimal nighttime repair. Other key ingredients include:
- Kola Seed Extract, Hydrolyzed Algae, and Chamomile for soothing benefits
- Hyaluronic Acid for deep hydration
- Antioxidants (Vitamins C and E) to protect against environmental damage
- Bifida Ferment Lysate (a probiotic) and peptides to boost repair and firmness
Together, these ingredients work to minimize visible signs of aging, hydrate the skin, and improve overall radiance.
Shiseido Ultimune Power Infusing Concentrate
This serum focuses on strengthening the skin barrier and improving resilience using a blend of plant-based and fermented ingredients:
- Fermented Roselle Extract to enhance moisture retention and skin plumpness
- Heartleaf Extract to soothe inflammation and boost protection
- Reishi Mushroom—rich in antioxidants—to hydrate and combat aging
The formula reflects Shiseido’s holistic approach to maintaining youthful, healthy skin through barrier support and stress defense.
Texture and Scent
Estee Lauder Advanced Night Repair
- Texture: Gel-like, slightly runny consistency that adheres well to skin without sliding
- Absorption: Fast-absorbing with a non-greasy finish, suitable for all skin types
- Scent: Virtually odorless, with a subtle, natural plant-based aroma
Shiseido Ultimune Power Infusing Concentrate
- Texture: Thick yet lightweight, with a silky, dewy finish that spreads easily
- Absorption: Leaves skin feeling smooth and protected, like an invisible veil
- Scent: Features a green floral fragrance enhanced with ImuCalm Compound™, including calming rose and lotus notes designed to ease emotional stress and uplift the senses
Pro Tip: Choose based on your preference—unscented formulas (Estee Lauder) or sensory experience (Shiseido).
How to Use Each Serum
Estee Lauder Advanced Night Repair
- When: Best used at night after cleansing and toning
- How: Apply a small amount to the face and neck, then follow with your nighttime moisturizer
- Best for: All skin types, especially mature or sensitive skin. Targets concerns like wrinkles, dullness, and uneven tone
Shiseido Ultimune Power Infusing Concentrate
- When: Use morning and night
- How: After cleansing and softening, apply before any other serums or moisturizers. Follow with your usual skincare routine
- Best for: All skin types, especially those dealing with environmental stress, fine lines, or loss of firmness
Layering Tip: Shiseido’s serum is designed to boost the effectiveness of any skincare routine, making it perfect as the first step in your serum application.
Price Comparison
Product | Size | Price (Approx.) |
Estee Lauder Advanced Night Repair | 30 mL | $105 |
Shiseido Ultimune Power Infusing Concentrate | 15 mL | $38 |
30 mL | $75 | |
50 mL | $110 | |
70 mL | $140 | |
70 mL (Refill) | $120 |
While Estee Lauder’s serum is priced higher for the 30 mL size, Shiseido offers more flexibility with various sizes, including a more budget-friendly 15 mL option.
Which Serum Should You Choose?
Choose Estee Lauder Advanced Night Repair if you:
- Want a trusted anti-aging serum that focuses on hydration and wrinkle reduction
- Prefer a formula that works best overnight
- Have mature, dry, or sensitive skin
- Appreciate a fragrance-free experience
Choose Shiseido Ultimune Power Infusing Concentrate if you:
- Need a serum that protects your skin from environmental stress
- Are looking to improve skin texture, firmness, and resilience
- Want a product that layers well with other skincare
- Enjoy a light, calming fragrance as part of your skincare ritual
Final Thoughts
Both Estee Lauder Advanced Night Repair and Shiseido Ultimune Power Infusing Concentrate are top-tier serums that deliver on their promises. The best choice depends on your skin needs, lifestyle, and budget.
- Go with Estee Lauder if you’re seeking powerful nighttime renewal and age-defying results.
- Opt for Shiseido if you’re looking for all-day protection and resilience with a sensory skincare experience.
Either way, you’re investing in scientifically developed skincare that enhances your skin’s health and appearance over time.