If you’re on the hunt for a high-performance serum that targets aging and enhances your skin’s radiance, chances are you’ve come across BIOEFFECT a luxury skincare brand from Iceland known for its revolutionary use of plant-based EGF (Epidermal Growth Factor). This powerful protein stimulates skin cell renewal, helping reduce fine lines, improve firmness, and promote a youthful glow.
Two of BIOEFFECT’s bestsellers—the EGF Serum and the EGF Power Serum—are often compared for their potent age-defying benefits. But what sets them apart, and which one is the better fit for your skincare routine?
In this in-depth comparison, we’ll explore the differences and similarities between these two EGF-packed serums to help you choose the one that aligns with your skin’s needs.
What We’ll Cover:
- Overview of BIOEFFECT EGF Serum and EGF Power Serum
- Key ingredients and formulation differences
- Texture and application
- Best usage scenarios
- Pricing breakdown
- Final verdict: Which one should you buy?
About BIOEFFECT EGF Serum & EGF Power Serum
Founded in Iceland, BIOEFFECT has earned global recognition for its minimalist, science-driven formulas featuring plant-based EGF bioengineered in barley. Their mission is to deliver effective, clean skincare that addresses visible signs of aging, such as dehydration, wrinkles, and uneven skin tone.
BIOEFFECT EGF Serum
This is the brand’s iconic flagship product, developed to hydrate, smooth, and restore the skin’s youthful appearance. With just 7 clean ingredients, this serum uses Barley EGF to boost collagen production, improve elasticity, and enhance moisture retention—making it ideal for daily use and early signs of aging.

BIOEFFECT EGF Power Serum
A more advanced version, the EGF Power Serum is formulated for those seeking intensive anti-aging results. It combines Barley EGF, Barley KGF (Keratinocyte Growth Factor), NAG (N-Acetyl Glucosamine), and Hyaluronic Acid to visibly reduce wrinkles, improve skin density, combat hyperpigmentation, and strengthen the skin barrier. It’s a concentrated formula designed to address five major signs of aging—with claims of improving them by up to ≥ 50%.

Ingredient Breakdown
EGF Serum
- Barley EGF – Stimulates skin cell renewal and collagen production
- Hyaluronic Acid – Deep hydration and plumping effect
- Barley Seed Extract – Antioxidant protection
- Icelandic Water – Pure, soft, mineral-light water
- Glycerin – Moisture-binding humectant
- Tromethamine & Sodium Chloride – Maintain pH balance and texture
With just 7 ingredients, this serum delivers hydration and skin regeneration in its purest form—free from alcohol, oil, fragrances, and preservatives.
EGF Power Serum
- Barley EGF – Supports cellular turnover and elasticity
- Barley KGF – A growth factor that strengthens the skin barrier
- N-Acetyl Glucosamine (NAG) – Helps reduce pigmentation and boosts hydration
- Hyaluronic Acid – Retains skin moisture
- Fragrance-free, paraben-free, silicone-free, gluten-free
With 12 carefully selected ingredients, the Power Serum offers a more robust and targeted solution for advanced signs of aging.
Texture & Absorption
EGF Serum
- Consistency: Extremely lightweight and water-like
- Feel: Absorbs quickly, leaves no residue
- User Experience: A few drops go a long way, ideal for layering or minimalist routines
This serum’s ultra-thin consistency may feel unusual at first, but it’s designed to optimize EGF absorption and performance.
EGF Power Serum
- Consistency: Light, silky, and slightly more substantial than the original
- Feel: Absorbs quickly with a smooth finish, no stickiness
- User Experience: Ideal for those wanting an intensive yet elegant anti-aging solution
Despite being more potent, the texture remains non-greasy and absorbs beautifully into the skin.
How to Use BIOEFFECT EGF Serum vs EGF Power Serum
EGF Serum Ideal For:
- Preventative skincare
- Daily hydration and collagen support
- Younger skin or those beginning their anti-aging journey
Usage Instructions:
- Apply 2–4 drops on clean, damp skin (face and neck)
- Use morning and night
- Best paired with EGF Essence, OSA Water Mist, or Imprinting Hydrogel Mask for enhanced results
EGF Power Serum Ideal For:
- Mature or aging skin
- Visible wrinkles, fine lines, pigmentation, or skin thinning
- Post-laser or post-peel recovery
Usage Instructions:
- Use 2–4 drops on the face, neck, and décolleté
- Apply in the morning (wait 3–5 minutes before moisturizer) and evening
- Can be layered with other BIOEFFECT products for enhanced results
Pro Tip: When using with non-BIOEFFECT products, allow up to 10 minutes of absorption time to ensure EGF and KGF efficacy.
Price Comparison
BIOEFFECT EGF Serum
- Price Range: $139 – $175 (depending on size and retailer)
BIOEFFECT EGF Power Serum
- Price Range: $219 – $297
The EGF Power Serum is priced higher due to its more complex formula, additional growth factors, and more targeted anti-aging benefits. However, both serums fall under premium skincare and reflect the brand’s biotech innovation.
Final Thoughts: Which BIOEFFECT Serum Should You Choose?
Both serums deliver excellent anti-aging results, thanks to Barley EGF and BIOEFFECT’s advanced biotechnology. The right choice ultimately depends on your skin condition and goals.
Choose EGF Serum if you:
- Prefer a minimalist formula with fewer ingredients
- Want to maintain healthy skin and prevent early signs of aging
- Are looking for a lightweight, daily-use serum
- Have sensitive or reactive skin that benefits from clean formulations
Choose EGF Power Serum if you:
- Are dealing with advanced signs of aging like wrinkles, uneven skin tone, or loss of firmness
- Need targeted treatment and faster results
- Have mature skin or are undergoing skin recovery (e.g., post-laser treatments)
- Want a more comprehensive anti-aging solution with multiple growth factors
Conclusion
Both BIOEFFECT EGF Serum and EGF Power Serum harness cutting-edge skin science to visibly improve your skin’s texture, elasticity, and overall radiance. Whether you’re focusing on prevention or looking for intensive treatment, there’s a powerful option tailored to your needs.
So, take stock of your current skin goals—whether it’s to preserve youthfulness or to reverse signs of aging—and let BIOEFFECT’s EGF technology guide your skincare journey toward healthier, more radiant skin.