If you’re on the hunt for premium skincare solutions, Shiseido is likely a brand you’ve come across. Known for its rich heritage and innovative technology, Shiseido offers a wide range of highly effective products tailored to various skin concerns. Two of its standout skincare items are the Shiseido Eudermine Activating Essence and the Ultimune Power Infusing Concentrate.
Both of these cult-favorite products are designed to enhance your skin’s appearance and texture—but they serve different purposes and contain unique ingredient profiles. In this guide, we’ll compare them in detail to help you determine which one fits your skincare needs.
What You’ll Learn:
- Overview of both Shiseido Eudermine Activating Essence and Ultimune Power Infusing Concentrate
- Key ingredient differences
- Texture and scent comparison
- Ideal usage for each product
- Price breakdown
- Final recommendation based on your skincare concerns
Product Overview
Shiseido is a leading Japanese skincare and cosmetics brand with over 140 years of innovation in beauty. With a strong focus on research and cutting-edge technology, the brand offers high-performance skincare lines that aim to deliver visible and lasting results.
Shiseido Eudermine Activating Essence
This hydrating lotion is formulated to activate the skin’s natural renewal process. It features two types of Hyaluronic Acid for deep, long-lasting hydration, and Vitamin C (Ethyl Ascorbic Acid) to brighten and even out skin tone. Designed for all skin types, it works to restore moisture, promote radiance, and improve overall skin texture.
Shiseido Ultimune Power Infusing Concentrate
This iconic serum is engineered to strengthen the skin’s defense system and protect it from environmental stressors and signs of aging. Using advanced Japanese skincare science, it combines powerful botanical extracts like fermented roselle, reishi mushroom, and heartleaf extract to hydrate, firm, and visibly improve skin resilience.
Key Ingredients Comparison
Shiseido Eudermine Activating Essence:
- Dual Hyaluronic Acid – Provides 24-hour hydration and helps retain moisture
- Ethyl Ascorbic Acid (Vitamin C) – Brightens complexion and improves skin tone
- Fermented Kefir Extract – Acts as a prebiotic to promote healthy skin turnover and strengthen the skin barrier
- Yuzu Extract – Boosts hydration levels
- ActiveRED Technology – Enhances ingredient absorption and eliminates impurities
- Scent – White floral base with Jasmine Sambac for an elegant, soothing experience
Shiseido Ultimune Power Infusing Concentrate:
- Fermented Roselle Extract – Boosts the skin’s moisture-holding capacity for a plumper appearance
- Heartleaf Extract – Calms and fortifies the skin barrier
- Reishi Mushroom – Rich in antioxidants to reduce signs of aging and provide deep hydration
- ImuCalm Compound™ – Contains lotus and rose elements to help relax the skin and combat damage caused by emotional stress
- Scent – Fresh green floral fragrance with calming aromatherapeutic effects
Texture and Scent
Shiseido Eudermine Activating Essence
- Texture: Rich and fluid, offering deep hydration without feeling heavy
- Feel: Leaves the skin soft, supple, and smooth with a firm finish
- Scent: Elegant white floral fragrance with a modern, luxurious vibe
Shiseido Ultimune Power Infusing Concentrate
- Texture: Thick yet dewy and lightweight upon application
- Feel: Glides smoothly and forms a silky barrier on the skin, creating a sensation of invisible protection
- Scent: Green floral with soothing, relaxing notes
Ideal Usage & Application
How to Use Shiseido Eudermine Activating Essence:
- When: Morning and evening, immediately after cleansing
- How: Apply a quarter-sized amount to Shiseido Facial Cotton or fingertips and smooth gently over the skin
- Best For: Dull, uneven skin tone, blemishes, and hydration support
How to Use Shiseido Ultimune Power Infusing Concentrate:
- When: After cleansing and softening, morning and evening
- How: Apply directly to face and neck as a serum before moisturizer
- Best For: Fine lines, wrinkles, loss of firmness, and environmental stress protection
Pro Tip: According to Shiseido, these two products can be used together for enhanced benefits. Start with Eudermine Activating Essence, followed by Ultimune Power Infusing Concentrate to layer hydration and protection.
Price Comparison
| Product | Size Options | Price Range |
| Eudermine Activating Essence | 145 mL | $90.00 (fixed size) |
| Ultimune Power Infusing Concentrate | 15 mL, 30 mL, 50 mL, 70 mL | $38.00–$140.00 |
| Ultimune (Refill – 70 mL) | $120.00 |
Verdict: While Eudermine Activating Essence comes in a single size, Ultimune Power Infusing Concentrate offers more flexibility with multiple size options, allowing you to choose based on your budget and needs.
Final Verdict: Which One Should You Choose?
Choosing between Shiseido Eudermine Activating Essence and Shiseido Ultimune Power Infusing Concentrate depends on your skincare goals.
Choose Eudermine Activating Essence if:
- You need long-lasting hydration and moisture retention
- You’re dealing with dullness, blemishes, or uneven skin tone
- You prefer a lightweight, refreshing essence that primes the skin
Choose Ultimune Power Infusing Concentrate if:
- You’re focused on anti-aging and environmental stress protection
- You’re concerned with fine lines, wrinkles, and skin firmness
- You want a thicker serum with intensive barrier-boosting benefits
Bonus Tip: For the best of both worlds, incorporate both products into your routine. Start with Eudermine for hydration and follow with Ultimune to protect and strengthen your skin barrier.
Conclusion
Both Shiseido Eudermine Activating Essence and Ultimune Power Infusing Concentrate offer powerful benefits in their own right. Whether you’re looking for radiant hydration or robust anti-aging protection, these two Shiseido favorites can elevate your skincare regimen. Consider your skin concerns and routine preferences—and don’t hesitate to combine both for optimal results.